Zarnestra developed by Johnson and Johnson Pharmaceutical Research and Development appears promising for the treatment of some patients with recurrent acute myeloid leukemia (AML), or for patients with AML who are not suitable candidates for more intensive therapy. Zarnestra is an inhibitant agent that is classified as a farnesyl transferase inhibitor and is still in clinical trials. It is estimated that 30% of leukemias have a mutated ras gene. The ras gene is a part of the biological pathwa...

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