Guanfacine is an oral and centrally acting, alpha2-adrenergic receptor agonist used alone or in combination with other drugs for the treatment of hypertension developed by Shire PLC.
It works by producing a decrease in sympathetic outflow, resulting in a reduction in peripheral vascular resistance, renal vascular resistance, heart rate, and also blood pressure.
Guanfacine is similar to clonidine but is more selective for alpha2-adrenergic receptors, longer-acting, dosed once d...
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