Myozyme (alglucosidase alfa) consists of the human enzyme acid alpha-glucosidase (GAA), encoded by the most predominant of nine observed haplotypes of this gene. Myozyme is formed by recombinant DNA technology in a Chinese hamster ovary cell line. Myozyme degrades glycogen by catalyzing the hydrolysis of alpha 1,4 and alpha 1,6 glycosidic linkages of lysosomal glycogen.

Myozyme is a glycoprotein with a calculated mass of 99,377 daltons for the polypeptide chain, and a total mass of a...

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